Seek medical help for diarrhea if it lasts over two days, is accompanied by severe abdominal pain, fever above 102°F, dehydration (dry mouth, dizziness, reduced urination), or blood in the stool. Persistent symptoms in children, elderly, or immunocompromised individuals require prompt attention. If diarrhea follows antibiotic use, like ceftriaxone wholesale, consult a doctor due to potential complications like Clostridium difficile infection. Dehydration is a serious risk, especially in vulnerable groups. Monitor for signs like sunken eyes or lethargy. Immediate care is crucial if symptoms worsen or don’t improve with home remedies like hydration and dietary changes. Always prioritize professional evaluation for severe cases.